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Publications

Scientific publications represent the heart of HEAL ITALIA‘s research.
Every paper tells the story of a discovery, an innovation, a step forward towards Precision Medicine accessible to all. The results are organised by Spoke, the eight thematic strands of the project: from the identification of biomarkers to innovative therapies, from early diagnosis to AI-supported clinical validation.

Artificial intelligence in endocrinology: a comprehensive review

F. Giorgini, G. Di Dalmazi & S. Diciotti
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NAADP-Evoked Ca2+ Signaling Leads to Mutant Huntingtin Aggregation and Autophagy Impairment in Murine Astrocytes

Cássia Arruda de Souza Pereira, Natalia de Castro Medaglia, Rodrigo Portes Ureshino, Claudia Bincoletto, Manuela Antonioli, Gian Maria Fimia, Mauro Piacentini, Gustavo José da Silva Pereira, Adolfo Garcia Erustes and...
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Personalised antiplatelet therapies for coronary artery disease: what the future holds

Davide Capodanno, Dominick J Angiolillo
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Aged mesenchymal stem cells and inflammation: from pathology to potential therapeutic strategies

Xue Yang, Ying Wang, Valentina Rovella, Eleonora Candi, Wei Jia, Francesca Bernassola, Pierluigi Bove, Mauro Piacentini, Manuel Scimeca, Giuseppe Sica, Giuseppe Tisone, Alessandro Mauriello, Lixin Wei, Gerry Melino, Yufang Shi
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Mixed β-γ-Cyclodextrin Branched Polymer with Multiple Photo-Chemotherapeutic Cargos

Francesca Laneri, Mimimorena Seggio, Cristina Parisi, Szabolcs Béni, Aurore Fraix, Milo Malanga, Salvatore Sortino
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Cost analysis of archives in the pathology laboratories: from safety to management

Albino Eccher, Angelo Paolo Dei Tos, Aldo Scarpa, Vincenzo L'Imperio, Enrico Munari, Giancarlo Tronco, Antonio Giuseppe Naccarato, Davide Seminati, Fabio Pagni
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Total Bio-Based Material for Drug Delivery and Iron Chelation to Fight Cancer through Antimicrobial Activity

Vincenzo Patamia, Chiara Zagni, Roberto Fiorenza, Virginia Fuoch, Sandro Dattilo, Paolo Maria Riccobene, Pio Maria Furneri, Giuseppe Floresta and Antonio Rescifina
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Assessing the relationship between cardiovascular and small airway disease and acute events in COPD: The ARCADIA study protocol

Paola Rogliani, Dejan Radovanovic, Josuel Ora, Nadia Starc, Stefano Verri, Elena Pistocchini, Luigino Calzetta
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A detailed mathematical model of the human atrial cardiomyocyte: integration of electrophysiology and cardiomechanics

Fazeelat Mazhar, Chiara Bartolucci, Francesco Regazzoni, Michelangelo Paci, Luca Dedè, Alfio Quarteroni, Cristiana Corsi, Stefano Severi
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Gene expression in organoids: an expanding horizon

Artem Smirnov, Gerry Melino & Eleonora Candi
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Chemotherapy-induced neutropenia elicits metastasis formation in mice by promoting proliferation of disseminated tumor cells

Massimo Russo, Nicolò Panini, Paola Fabbrizio, Laura Formenti, Riccardo Becchetti, Cristina Matteo, Marina Meroni, Claudia Nastasi, Andrea Cappelleri, Roberta Frapolli, Giovanni Nardo, Eugenio Scanziani, Andrea Ponzetta, Maria Rosa Bani, Carmen...
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Delta-radiomics in cancer immunotherapy response prediction: A systematic review

Engy Abbasa, Salvatore Claudio Fanni, Claudio Bandini, Dania Cioni, Riccardo Antonio Lencioni, Emanuele Neria...
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In silico analysis and theratyping of an ultra-rare CFTR genotype (W57G/A234D) in primary human rectal and nasal epithelial cells

Karina Kleinfelder, Virginia Lotti, Adriana Eramo, Marco Lucarelli, Paola Melotti, Claudio Sorio...
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Interpretation and management of premature ventricular beats in athletes: An expert opinion document of the Italian Society of Sports Cardiology

Alessandro Zorzia, Flavio D'Ascenzi, Daniele Andreini, Patrizio Sarton, Domenico Corrado, Luigi Sciarra...
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Modeling Zeta Potential for Nanoparticles in Solution: Water Flexibility Matters

Paulo Siani, Giulia Frigerio, Edoardo Donadoni, Cristiana Di Valentin
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Altered Thyroid Feedback Loop in Klinefelter Syndrome: From Infancy Through the Transition to Adulthood

Francesco Carlomagno, Marianna Minnetti, Francesco Angelini, Riccardo Pofi, Emilia Sbardella, Matteo Spaziani, Alessia Aureli, Antonella Anzuini, Roberto Paparella, Luigi Tarani...
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ZNF750: A Novel Prognostic Biomarker in Metastatic Prostate Cancer

Manuela Montanaro, Massimiliano Agostini, Lucia Anemona, Elena Bonanno, Francesca Servadei, Enrico Finazzi Agrò, Anastasios D. Asimakopoulos, Carlo Ganini, Chiara Cipriani, Marta Signoretti, Pierluigi Bove, Francesco Rugolo, Benedetta Imperiali, Gerry Melino,...
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Circulating metabolites improve the prediction of renal impairment in patients with type 2 diabetes

Vincenzo Trischitta, Mario Mastroianno, Maria Giovanna Scarale, Cornelia Prehn, Lucia Salvemini, Andrea Fontana...
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Er:Y2O3 and Nd:Y2O3 Nanoparticles: Synthesis, Pegylation, Characterization and Study of Their Luminescence Properties

Regina Maria Chiechio, Rosalia Battaglia, Angela Caponnetto, Ester Butera, Giorgia Franzò, Riccardo Reitano, Michele Purrello, Marco Ragusa, Davide Barbagallo, Cristina Barbagallo, Cinzia Di Pietro, Valérie Marchi, Maria José Lo Faro,...
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Sex hormones differentially contribute to Parkinson disease in males: A multimodal biomarker study

Roberta Bovenzi, Giulia Maria Sancesario, Matteo Conti, Piergiorgio Grillo, Rocco Cerroni, Jacopo Bissacco, Paolo Forti, Emilia Giannella, Massimo Pieri, Silvia Minosse, Valentina Ferrazzoli...
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ICGC ARGO precision medicine: genomic profiling-informed prediction of immunotherapy response in two patients with metastatic head and neck squamous cell carcinoma

Riccardo Nocini, Luca Tondulli, Consuelo D'Ambrosio, Claudio Luchini, Andrew V Biankin, Raffaella Casolino
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Insights into the Structural Conformations of the Tau Protein in Different Aggregation Status

Luca Pinzi, Nicolò Bisi, Claudia Sorbi, Silvia Franchini, Nicolò Tonali and Giulio Rastelli
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To metabolomics and beyond: a technological portfolio to investigate cancer metabolism

Federica Danzi, Raffaella Pacchiana, Andrea Mafficini, Maria T. Scupoli, Aldo Scarpa, Massimo Donadelli, Alessandra Fiore
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Advancing the PD-L1 CPS test in metastatic TNBC: Insights from pathologists and findings from a nationwide survey

Nicola Fusco, Mariia Ivanova, Chiara Frascarelli, Carmen Criscitiello, Bruna Cerbelli, Maria Gemma Pignataro, Angelina Pernazza, Elham Sajjadi, Konstantinos Venetis, Giulia Cursano, Fabio Pagni, Camillo Di Bella, Marina Accardo, Michelina Amato,...
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