Publications

Scientific publications represent the heart of HEAL ITALIA‘s research.
Every paper tells the story of a discovery, an innovation, a step forward towards Precision Medicine accessible to all. The results are organised by Spoke, the eight thematic strands of the project: from the identification of biomarkers to innovative therapies, from early diagnosis to AI-supported clinical validation.

2023

Anti-tumor activity of all-trans retinoic acid in gastric-cancer: gene-networks and molecular mechanisms

Luca Guarrera, Mami Kurosaki, Silvio-Ken Garattini, Maurizio Giannì, Gianpiero Fasola, Luca Rossit, Michele Prisciandaro, Maria Di Bartolomeo, Marco Bolis, Paola Rizzo, Claudia Nastasi, Marika Foglia, Adriana Zanetti, Gabriela Paroni, Mineko...

Publications

Anti-tumor activity of all-trans retinoic acid in gastric-cancer: gene-networks and molecular mechanisms

Ca2+ signaling and cell death

Microbiota-gut-brain axis: relationships among the vagus nerve, gut microbiota, obesity, and diabetes

Antineoplastic drugs inducing cardiac and vascular toxicity – An update

Apoptotic cell death in disease—Current understanding of the NCCD 2023

Noninvasive assessment of liver disease severity in patients with nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes

Artificial intelligence-based models to assess the risk of malignancy on radiological imaging in patients with intraductal papillary mucinous neoplasm of the pancreas: scoping review

ZFP750 affects the cutaneous barrier through regulating lipid metabolism

High-risk TP53 mutations predict poor primary treatment response of patients with head and neck squamous cell carcinoma

The Immune Cells in the Development of Oral Squamous Cell Carcinoma

L1077P CFTR pathogenic variant function rescue by Elexacaftor–Tezacaftor–Ivacaftor in cystic fibrosis patient-derived air–liquid interface (ALI) cultures and organoids: in vitro guided personalized therapy of non-F508del patients

Programmed cell death 1 genetic variant and liver damage in nonalcoholic fatty liver disease

Characterization of a novel IDH2-R159H mutation in acute myeloid leukaemia: Effects on cell metabolism and differentiation

Recapitulating thyroid cancer histotypes through engineering embryonic stem cells

Metadynamics simulations for the investigation of drug loading on functionalized inorganic nanoparticles

In Vitro Models of Bacterial Biofilms: Innovative Tools to Improve Understanding and Treatment of Infections

Clinical and neurochemical correlates of the APOE genotype in early-stage Parkinson’s disease

Expression profiling of extramedullary acute myeloid leukemia suggests involvement of epithelial–mesenchymal transition pathways

Trends and Applications in Computationally Driven Drug Repurposing

A BPMN-based Framework to Manage ERAS-inspired Pathway for Patients Undergoing Pancreatic Surgery

Altered pathways of keratinization, extracellular matrix generation, angiogenesis, and stromal stem cells proliferation in patients with systemic sclerosis

Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms

Metabolic regulation by p53 prevents R-loop-associated genomic instability

Transglutaminase type 2-dependent crosslinking of IRF3 in dying melanoma cells

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