Publications

Scientific publications represent the heart of HEAL ITALIA‘s research.
Every paper tells the story of a discovery, an innovation, a step forward towards Precision Medicine accessible to all. The results are organised by Spoke, the eight thematic strands of the project: from the identification of biomarkers to innovative therapies, from early diagnosis to AI-supported clinical validation.

A Migration Framework for Active BPMN Processes in Healthcare

Matteo Mantovani, Emanuele Chini, Carlo Combi
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Pre-scleroderma and new opportunities for preventive medicine

Devis Benfaremoa, Chiara Tanac, Gianluca Moroncini
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Optimizing Transfection Efficiency in CAR-T Cell Manufacturing through Multiple Administrations of Lipid-Based Nanoparticles

Francesca Giulimondi, Luca Digiacomo, Serena Renzi, Chiara Cassone, Andrea Pirrottina, Rosa Molfetta, Ilaria Elena Palamà, Gabriele Maiorano, Giuseppe Gigli, Heinz Amenitsch, Daniela Pozzi, Alessandra Zingoni, Giulio Caracciolo
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Novel half Salphen cobalt(iii) complexes: synthesis, DNA binding and anticancer studies

Riccardo Bonsignore, Elisa Trippodo, Roberto Di Gesù, Anna Paola Carreca, Simona Rubino, Angelo Spinello, Alessio Terenzi and Giampaolo Barone
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Regenerative Medicine / Mesenchymal Stem Cells | The miRNA Contribution in Adipocyte Maturation

Alessandro Giammona, Simone Di Franco, Alessia Lo Dico and Giorgio Stassi
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First-hit SETBP1 mutations cause a myeloproliferative disorder with bone marrow fibrosis

Ilaria Crespiatico, Mattia Zaghi, Cristina Mastini, Deborah D’Aliberti, Mario Mauri, Carl Mirko Mercado, Diletta Fontana, Silvia Spinelli, Valentina Crippa, Elena Inzoli, Beatrice Manghisi, Ivan Civettini, Daniele Ramazzotti, Valentina Sangiorgio, Michele...
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Initial management approach for localized/locally advanced disease is critical to guide metastatic castration-resistant prostate cancer care

Vincenza Conteduca, Piergiorgio Di Tullio, Rossana Allamprese, Giuseppina Bruno, Cristian Lolli, Giuseppe Schepisi, Aldo Rosano, Guido Giordano, Marianna Garofoli, Vincenzo Emanuele Chiuri, Lucia Fratino, Elisa Zanardi, Luca Galli, Francesco Massari,...
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Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity

Vanessa Yu, Fiona Yong, Angellica Marta, Sanjay Khadayate, Adrien Osakwe, Supriyo Bhattacharya, Sneha S. Varghese, Pauline Chabosseau, Sayed M. Tabibi, Keran Chen, Eleni Georgiadou, Nazia Parveen, Mara Suleiman, Zoe Stamoulis,...
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Harnessing metabolism of hepatic macrophages to aid liver regeneration

Rui Liu, Manuel Scimeca, Qiang Sun, Gerry Melino, Alessandro Mauriello, Changshun Shao, TOR Centre, Yufang Shi, Mauro Piacentini, Giuseppe Tisone & Massimiliano Agostini
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  • Network 2 - Intelligent Health

Investigation of a potential upstream harmonization based on image appearance matching to improve radiomics features robustness: a phantom study

Camilla Scapicchio, Manuela Imbriani, Francesca Lizzi, Mariagrazia Quattrocchi, Alessandra Retico, Sara Saponaro, Maria Irene Tenerani, Alessandro Tofani, Arman Zafaranchi and Maria Evelina Fantacci
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Atrial natriuretic peptide stimulates autophagy/mitophagy and improves mitochondrial function in chronic heart failure

Salvatore Raffa, Maurizio Forte, Giovanna Gallo, Danilo Ranieri, Simona Marchitti, Damiano Magrì, Marco Testa, Rosita Stanzione, Franca Bianchi, Maria Cotugno, Emiliano Fiori, Vincenzo Visco, Sebastiano Sciarretta, Massimo Volpe, Speranza Rubattu
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Red-Light-Photosensitized NO Release and Its Monitoring in Cancer Cells with Biodegradable Polymeric Nanoparticles

Aurore Fraix Cristina Parisi Giuseppe Longobardi Claudia Conte Arianna Pastore Mariano Stornaiuolo Adriana C. E. Graziano Marta E. Alberto Antonio Francés-Monerris Fabiana Quaglia, Salvatore Sortino
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Oesophageal varices predict complications in compensated advanced non-alcoholic fatty liver disease

Grazia Pennisi, Marco Enea, Mauro Viganò, Vito Di Marco, Calogero Cammà, Salvatore Petta
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Sustainable Vegetable Oil-Based Biomaterials: Synthesis and Biomedical Applications

Chiara Nurchi, Silvia Buonvino, Ilaria Arciero and Sonia Melino
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Value of Artificial Intelligence in Evaluating Lymph Node Metastases

Nicolò Caldonazzi, Paola Chiara Rizzo, Albino Eccher, ,Ilaria Girolami , Giuseppe Nicolò Fanelli, Antonio Giuseppe Naccarato, Giuseppina Bonizzi, Nicola Fusco, Giulia d’Amati ,Aldo Scarpa, Liron Pantanowitz and Stefano Marletta
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Autophagy, innate immunity, and cardiac disease

Donato Santovito, Sabine Steffens, Serena Barachini, Rosalinda Madon na
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Lactobacillus rhamnosus GG cell-free supernatant as a novel anti-cancer adjuvant

Rossella Salemi, Silvia Vivarelli, Daria Ricci, Marina Scillato, Maria Santagati, Giuseppe Gattuso, Luca Falzone & Massimo Libra
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A novel complement-fixing IgM antibody targeting GPC1 as a useful immunotherapeutic strategy for the treatment of pancreatic ductal adenocarcinoma

Davide Busato, Sara Capolla, Paolo Durigutto, Monica Mossenta, Sara Bozzer, Daniele Sblattero, Paolo Macor, Michele Dal Bo & Giuseppe Toffoli
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Decline of gastric cancer mortality in common variable immunodeficiency in the years 2018-2022

Cinzia Milito, Federica Pulvirenti, Giulia Garzi, Eleonora Sculco, Francesco Cinetto, Davide Firinu, Gianluca Lagnese, Alessandra Punziano, Claudia Discardi, Giulia Costanzo, Carla Felice Carla, Giuseppe Spadaro, Simona Ferrari, Isabella Quinti
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Type 2 transglutaminase in the nucleus: the new epigenetic face of a cytoplasmic enzyme

Federica Rossin, Fabiola Ciccosanti, Manuela D'Eletto, Luca Occhigrossi, Gian Maria Fimia & Mauro Piacentini
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Anatomical Study of the Application of a Galeo-Pericranial Flap in Oral Cavity Defects Reconstruction

Alice Marzi Manfroni, Maria Vittoria Marvi, Simone Lodi, Cyril Breque, Giulio Vara, Alessandra Ruggeri, Giovanni Badiali, Lucia Manzoli, Achille Tarsitano and Stefano Ratti
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The STING/TBK1/IRF3/IFN type I pathway is defective in cystic fibrosis

Luca Occhigrossi, Federica Rossin, Valeria Rachela Villella, Speranza Esposito, Carlo Abbate, Manuela D'Eletto, Maria Grazi, Antonella Tosco, Roberta Nardacci Gian Maria Fimia, Valeria Raia, Mauro Piacentini
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Serine and one-carbon metabolism sustain non-melanoma skin cancer progression

Angela Cappello, Alessandro Zuccotti, Mara Mancini, Giulia Tosetti, Luca Fania, Francesco Ricci, Gerry Melino & Eleonora Candi
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Benzodiazepine diazepam regulates cell surface β1-adrenergic receptor density in human monocytes

Paola Matarrese, Sonia Maccari, Lucrezia Gambardella, Rosa Vona, Federica Barbagallo, Vanessa Vezzi, Tonino Stati, Maria Cristina Grò, Antonello Giovanneti, Liviana Catalano, Paola Molinari, Giuseppe Marano, Caterina Ambrosio
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